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  • Name: YDL223C
  • * CAS #: 489408-02-8
  • 上架时间: 2019-10-10
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2-(((5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetyl)amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, N-[3-(Aminocarbonyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-5-methyl-3-(trifluoromethyl)-1H-pyrazole-1-acetamide,
2-(((5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetyl)amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
 
489408-02-8
Systematic Name:
YDL223C
 
C16H17F3N4O2S
Molecular Weight: 386.39
CAS Number: 489408-02-8
 
Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, H
assay  ≥98% (HPLC)
form  powder
color  white to beige
solubility  DMSO: 2 mg/mL, clear
storage temp.  2-8°C
 
HBT1 is an AMPA-R [alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor] potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate dependent manner.
Shmoo tip protein, substrate of Hub1p ubiquitin-like protein; mutants are defective for mating projection formation, thereby implicating Hbt1p in polarized cell morphogenesis; HBT1 has a paralog, YNL195C, that arose from the whole genome duplication
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