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O-304 | 1261289-04-6 98%


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  • O-304 | 1261289-04-6 98%
  • 1261289-04-6
  • C16H11Cl2N3O2S
  • 380.25
  • 98%
  • White to off-white powder
  • 1kg/bag, 25kg/barrel
  • Build Muscle & Weight Management
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O-304  CAS No.:1261289-04-6  Build muscle and lose fat.

1. Product parameters

Product name

O-304

Other name

 4-Chloro-N-[2-[(4-chlorophenyl)methyl]-2,3-dihydro-3-oxo-1,2,4-thiadiazol-5-yl]benzamide

CAS No.

1261289-04-6

Molecular formula

C16H11Cl2N3O2S

Molecular weight

380.25

Purity

98%

Appearance

White to off-white powder

Packing

1kg/bag, 25kg/barrel

Application

Dietary Supplement Raw Material

2. Product introduction

O-304 is a small-molecule AMPK activator that enhances AMPK activity by inhibiting the dephosphorylation of phosphorylated AMPK (pAMPK), thereby increasing pAMPK levels without reducing intracellular adenosine triphosphate (ATP) concentrations. It possesses multiple mechanisms of action, including improving glucose metabolism, reducing insulin resistance, and protecting the cardiovascular system.

3. Feature

(1) High purity: O-304 is produced through a refined manufacturing process, achieving high product purity.  High purity means better bioavailability.

(2) Biological Activity: O-304 is an orally active pan-activator of AMPK (AMP-activated protein kinase). It enhances AMPK activity by inhibiting the dephosphorylation of pAMPK.

4. Applications

  1. AMPK Activation: O-304 increases AMPK activity by inhibiting the dephosphorylation process of phosphorylated AMPK (pAMPK), thereby regulating energy metabolism balance.
  2. Improving glucose metabolism: In animal studies, a dose of 100 mg/kg of O-304 effectively helped maintain stable fasting blood glucose and plasma insulin levels, significantly reducing the metabolic burden caused by a high-fat diet, and preventing blood glucose fluctuations and abnormal insulin elevation triggered by dietary imbalances.
  3. Protecting vascular elasticity: O-304 helps maintain blood pressure at healthy levels, reduces stress on blood vessels, and provides long-term, gentle protection for the cardiovascular and cerebrovascular systems, supporting emotional stability and sustained energy.
  4. Promoting lasting youthfulness: O-304 precisely targets the AMPK-mTOR signaling pathway, intelligently regulating the process of cellular autophagy, promoting the catabolism of aged proteins and abnormal lipids, and maintaining a clean and vibrant cellular environment, thereby delaying cellular aging.

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